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Question & Answer

Questions About Genetics MyHappyGenes is dedicated to helping individuals achieve healthy outcomes through knowledge of DNA and Genetics. By understanding your DNA you can better understand your health outcomes. Here are a couple of articles we have written on that subject. Genetics Determine Your Best Diet Everyone knows people who can eat whatever they like, […]

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Genetics of Populations as Related to Health and Disease

Specific diseases and health issues can be directly connected to the genetics of populations. The distribution of genetic variations differ greatly among human populations. This is largely due to their historical patterns of mutation, migration, reproduction, mating, selection, and genetic drift. Inherited mutations usually occur during gametogenesis within a single individual and eventually passed onto

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Studies on Genetic Variation and Risks

One of the main reasons for studying the origins and nature of human genetic variation is that the similarities and differences in the type and frequencies of genetic variations among populations can have a profound impact on studies that attempt to understand the influence of genes on disease risk.  For example, some genetic variations, like


Pharmacogenetics is the study of how people respond to drug therapy. Through research and multiple studies, it has been confirmed that individuals often respond differently to the same drug therapy. This is typically due to one’s genetic makeup, but overall health, diet, and environmental factors also play a significant role in how a person responds

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Health Influenced by Genetics

Health is greatly influenced by one’s genetics. Nearly every cell in the body carries an entire genome full of variations as the template for the development of its protein machinery. Therefore, it can be said that genetic variations impact all cellular, biochemical, physiological, and morphological aspects of a human being. For this reason, the majority

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Sickle Cell Disease- A Single-Gene Disorder

A prime example of a single-gene disorder is sickle cell disease. This refers to an autosomal recessive blood disorder caused by a variant of the β-globin gene called sickle hemoglobin (Hb S).  With sickle cell disease, a single nucleotide substitution (T→A) in the sixth codon of the β-globin gene results in the substitution of valine

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Genetic Susceptibility

Genetic susceptibility refers to a person’s increased chance of developing a particular disease based on their genetic makeup.Inherited genetic variation has been studied for over 100 years. Geneticists examine how different genes can increase a person’s risk of developing certain diseases.  Genetic susceptibility studies have been done in two ways with different points of focus.

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Understanding the COMT Gene

Are you struggling with health problems? Do you wonder if they are genetic? Understanding the COMT gene can give you cality. While it’s usually a combination of genes that make you more likely to have a health issue, there are certain genes that make you more susceptible to health problems. Specific genes can have a

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Gene-Environment & Gene-Gene Interactions

Studies of genetic connections can be represented by gene-environment and gene-gene interaction studies. These classes of genetic relationships focus on understanding how human genetic variability can be linked to a variety of responses to exposures to different environmental aspects. These effects can also vary depending on differences in other genes.  Gene-environment interactions can be highlighted

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Genetic Linkage & Association Studies

Designating a specific gene to disease is a meticulous and methodical process as the human genome is made of tens of thousands of individual genes. Gene discovery typically begins with an analysis of the genetic linkage which assesses diseases within families. Genetic association studies follow linkage analyses in order to assess diseases across families and