Pharmacogenetics is the study of how people respond to drug therapy. Through research and multiple studies, it has been confirmed that individuals often respond differently to the same drug therapy. This is typically due to one’s genetic makeup, but overall health, diet, and environmental factors also play a significant role in how a person responds …
Studies on cardiovascular disease (CVD) can be used to highlight the problems that occur in using genetic information to understand the etiology of some of the most common chronic diseases. These studies on cardiovascular disease (CVD) are also used to help identify those at the highest risk of developing CVD. Most cardiovascular disease (CVD) cases …
A prime example of a single-gene disorder is sickle cell disease. This refers to an autosomal recessive blood disorder caused by a variant of the β-globin gene called sickle hemoglobin (Hb S). With sickle cell disease, a single nucleotide substitution (T→A) in the sixth codon of the β-globin gene results in the substitution of valine …
Immunity plays an important role in the defense against infection. Studies by several investigators based on this hypothesis led to the recognition that there is a common link between malignancies
