My Happy Genes - ADD Relief

Repairing DNA with Methylation

MyHappyGenes, We use state of the art tools in Genetics and Bioinformatics to produce thoroughly curated, easy to understand genetic reports that can be used by professional practitioners as well as individuals.

In her book, Dr. J. Dunn explores issues into why you are the way you are and how you can make changes. It’s a whole new paradigm in understanding what causes disease and mental health issues. The basis of the book talks about how to bypass your genetic makeup to help change destructive behaviors such as overeating, substance abuse, and anger. She goes further to explain repairing DNA with methylation:

“Methylation – The search for what exactly helps the body make glutathione leads back to the biochemistry textbooks that physicians’ study in graduate school.  The methylation pathway, called the methylation cycle, did not receive much attention in the past. In chiropractic school, teachers put a lot of emphasis on a pathway called the Krebs cycle, but I don’t even remember talking about the methylation cycle.  Yet, as I began to do more research, it seemed to me to be one of the most critical pathways in the body for health and preserving life. 

The methylation pathway is responsible for repairing DNA, as well as for detoxifying the body of chemicals, metals, pesticides, hormones, and neurotoxins.  It is responsible for creating hormones, neurotransmitters (brain chemicals), and stress hormones; it also facilitates immune system function (specifically T cell production), nitric oxide formation, free radical quenching, and energy production.  

As I began to study Dr. Yasko’s work and her research which involved testing the DNA of her autistic patients, I realized that she was probably on to something.  She observed a small number of genetic variants that could cause “blocks” in the methylation pathway. These genetic blocks would prevent the children from eliminating heavy metals correctly and would make them susceptible to damage from vaccines containing mercury or aluminum.  In addition, the blocks prevented them from eliminating neurotoxins such as glutamate, which would then accumulate and cause neurological damage.  

This research clarified the reason why not all children who get vaccinated will get autism.  Not all children have genetic variants that put them at risk. This insight explains why medical experts have not been able to demonstrate a truly causative association between autism and vaccines.  Whether the person succumbs to the side effects of vaccines or not really depends on the genes of the person getting the shots and also their varying levels of tolerance. One-shot may not cause problems, but several in a row or given together could throw these children into acute reactions and lead to autistic behaviors at varying levels.  The autistic spectrum is a wide spectrum. It can include manifestations ranging from antisocial behavior to a full-blown inability to function in the world. 

Defects in methylation can interact with environmental and infectious agents, resulting in a wide range of conditions and diseases.  These illnesses include diabetes, cardiovascular disease, thyroid dysfunction, neurological inflammation, chronic viral infections, neurotransmitter imbalances, atherosclerosis, and cancer.  Other infirmities that could result include aging, schizophrenia, autism, Alzheimer’s disease, decreased repair of tissue damage, improper immune function, neural tube defects, Down’s syndrome, MS, ADHD/ADD, Huntington’s disease, and Parkinson’s disease.

Not every individual who has genetic variants in methylation will develop one of these health conditions.  Genetic variants present potential problems. As mentioned above, an environmental or infectious agent may sometimes trigger the disease process.  Most health conditions in society are multifactorial in nature. A certain threshold or body burden needs to exist in order for one of these diseases to manifest.  However, part of what makes this methylation cycle so critical is that variations in the cycle itself can cause the body to retain heavy metals or toxins that can trigger one of these diseases.  Environmental toxic burdens themselves can be harmful not only to the body but also can have adverse secondary effects on genetic expression. 

Having a certain risk for a genetically-associated health concern such as cancer or heart disease does not mean you will necessarily acquire it.  These genes must be “turned on” to cause the expression of the disease. For instance, when we are exposed to toxic substances such as chemicals, pesticides or radiation, it can “turn on” the expression of a gene and begin the formation of a tumor. For instance, cigarette smoking can cause the expression of the genes that are associated with lung cancer. People who do not have that gene may be unaffected by smoking.  We all know folks who “get away” with bad behavior that can be risky for others. This is often due to their genetic risk factors. “


In this book we will explore such issues, and, hopefully, you will gain insight into why you are the way you are and how you can become who you want to be through understanding and working with your unique genetic blueprint.  Insights presented from the new genetic research can teach you to have greater compassion for yourself and others; it can show you how to achieve levels of health that you may never have experienced. Not only that, you may find guidance that shows you how to support your body in ways that keep you from expressing those genes that may potentially lead to dis-ease.  This is a whole new paradigm in understanding health and the causes of disease and mental health issues.

Dr. J. Dunn explains how her research was motivated because of her personal struggles to feel healthy. She had a case of mono when she was sixteen years old and suffered from lifelong depression. Since then she has battled chronic fatigue syndrome caused by the Epstein-Barr virus (EBV). Looking into the history of the virus she found that 90 percent or more people have antibodies to the virus and yet don’t necessarily have an issue with it for the rest of their lives. She was also looking for true answers to her own depression. These were missing pieces in the puzzle of health, and she began her quest to search for why and how to fix them. She approached her research with a compassionate point of view, knowing that some types of behavior and health problems are caused by inherited biochemical imbalances and are not personal failings. Things such as:

Focusing Issues such as ADD and ADHD
Chronic Fatigue

Genetic testing can identify potential health problems and give you another tool to make informed decisions about managing your health care. Dr. J. Dunn explores how to obtain correct results and what to do with the results. She also talks about compassion for yourself and others when it comes to problems beyond our control. Her book – Genetic Compassion – will help you to understand how genes play a very important role in how we feel.