Functional Genetics in Practice

Clinical insights for practitioners working at the intersection of genetics, nutrition, and personalized care

Cardiovascular disease remains the leading cause of death globally, yet its genetic underpinnings are frequently underaddressed in functional medicine practice. Patients arrive having been told

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If you're working with patients who present with complex, multi-system complaints that don't resolve with standard protocols, a CBS upregulation variant is worth investigating early.

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Mitochondrial dysfunction shows up constantly in practice — fatigue that doesn't respond to sleep, poor exercise recovery, brain fog, mood symptoms that don't improve with

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Alcohol Intolerance in Practice: What the Genetic Variants Are Really Telling You "I used to be able to have two glasses of wine, now one

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Histamine intolerance is one of the most frequently missed diagnoses in functional medicine practice. Patients present with a constellation of symptoms that seem unrelated —

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Of all the genetic variants affecting immune function on the MyHappyGenes® report, VDR — the vitamin D receptor gene — has the broadest and most

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Autoimmune presentations are rarely explained by a single gene or pathway. When VDR optimization and foundational methylation support have been addressed and patients are still

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MAO-A is one of the most clinically impactful genes on the MyHappyGenes® report and one of the most misunderstood. Patients with MAO-A variants frequently arrive

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MTHFR is arguably the most researched gene in functional medicine — and arguably the most misapplied. The clinical literature is robust, the patient awareness is

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Of all the genes on the MyHappyGenes® report, COMT is one of the most clinically significant and one of the most frequently mismanaged. Its effects

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