DNA Mechanical Workings MyHappyGenes

Sickle Cell Disease- A Single-Gene Disorder

A prime example of a single-gene disorder is sickle cell disease. This refers to an autosomal recessive blood disorder caused by a variant of the β-globin gene called sickle hemoglobin (Hb S).  With sickle cell disease, a single nucleotide substitution (T→A) in the sixth codon of the β-globin gene results in the substitution of valine …

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Genetic Susceptibility

Genetic susceptibility refers to a person’s increased chance of developing a particular disease based on their genetic makeup.Inherited genetic variation has been studied for over 100 years. Geneticists examine how different genes can increase a person’s risk of developing certain diseases.  Genetic susceptibility studies have been done in two ways with different points of focus. …

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Gene-Environment & Gene-Gene Interactions

Studies of genetic connections can be represented by gene-environment and gene-gene interaction studies. These classes of genetic relationships focus on understanding how human genetic variability can be linked to a variety of responses to exposures to different environmental aspects. These effects can also vary depending on differences in other genes.  Gene-environment interactions can be highlighted …

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Your Genes Control Brain Chemistry and Health

What Causes Depression?

An age-old question that has been asked and answered by people far and wide. Over time, our idea of what causes a person to have depression has changed a lot. Hundreds of years ago, the popular belief was that depression was caused by demons.

Questions And Answers to Genetics and DNA

Human Genome Q & A

The human genome project was a huge undertaking.  Researchers set about labeling and identifying all the genes of the human body which number in the billions. This information includes statistics about your ancestry and family origins, as well as contact information to reach blood relatives you may not have known exist.

Questions And Answers to Genetics and DNA

Q&A About Genetics

How Genes Play a Role in Disease and Health

When slight changes occur in genes, it can cause susceptibility to many common diseases, including cancer, obesity, diabetes, heart disease, and mental illness. Genetic predisposition and the risk of disease can depend on multiple factors in addition to genetic changes.